Identification of Barbiturates

The identification of barbiturates by paper chromatography.

B ECAUSE barbiturates are relatively easily available and much used drugs, specimens from suspected cases of poisoning are frequently submitted to the laboratory for routine chemical examination. Since their urinary excretion begins early (because they are quickly absorbed), they can often be identified 1-2 hours after administration. The specimen of choice for examination is therefore the urin...

Identification of Barbiturates by Thin-layer Chromatography.

in cases of overdose and identification of the actual barbiturate concerned may be impossible because of the closely similar Rf values of this group. Jackson (1960) described treatment with hot sulphuric acid before paper chromatography to distinguish between barbiturates of similar chromatographic mobility. The inert nature of the silica gel supporting medium used in thin-layer separations ena...

The identification and determination of barbiturates in serum.

Acta pharmacol. toxicol, 3, 165 (1947). — 14. DELBR CK, A., F. HARTMANN und R. SCHNEIDER, Med. Klin. 58, 376 (1963). — 15. JuNCE-H LSiNG, G., pers. Mitt. — 16. ASBOE-HANSEN, G., Physiol. Rev. 38, 446 (1958). —17. DORFMAN, A. und S. SCHILLER, Recent Progr. Hormone Res. 14y 427 (1958). — 18. BEIERWALTES, W. H. und A. J. SOLLET, J. Clin. Invest. 38, 945 (1959). — 19. GABRILOOE, J. L. und A. W. LUD...

Identification of Barbiturates in Blood by Paper Chromatography.

S TATISTICS conmpiled by time l’oison Control Center, New York City Department of Heaitlm, indicate fimat barbiturate imitoxication in adults ranks first as a cause of poisonilmg (1). The need for a rapid and sensitive method for detecting ammd ideiitifyiimg barbiturates in body fluids for diagnostic purpose is obvious. Even though timere Imave been mamiy analytic methods described in recelmt y...

Barbiturates.